KDM4A Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesJMJD2; JHDM3A; JMJD2A; KIAA0677; KDM4A
ProductOrderK
Clone#5H1
Entrez GenelD9682
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human KDM4A expressed in E. Coli.
MW120kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
500-705
Catalog#: 30087
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Images
Western Blot
Figure 1: Western blot analysis using KDM4A mAb against HEK293 (1) and KDM4A(AA: 500-705)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 1: Western blot analysis using KDM4A mAb against HEK293 (1) and KDM4A(AA: 500-705)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human larynx cancer tissues (right) using KDM4A mouse mAb with DAB staining.
Immunofluorescence analysis
Figure 3: Immunofluorescence analysis of NTERA-2 cells using KDM4A mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 3: Immunofluorescence analysis of NTERA-2 cells using KDM4A mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Product Overview
Description

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

References (references)
References (references)1. Genome Res. 2004 Sep;14(9):1711-8.
2. Nat Methods. 2005 Aug;2(8):591-8.
3. Cell. 2006 May 19;125(4):691-702.