KAT7 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31673 100μg $341.00
Specification
AliasesHBO1; HBOA; MYST2; ZC2HC7
Clone#4E12H12
Entrez GeneID11143
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human KAT7 (AA: 1-200) expressed in E. Coli.
MW70.6kDa
Species ReactivityHuman, Mouse, Monkey
Application
ELISA1/10000
Sequence
1-200
Catalog
31673
$341.00
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Images

Elisa

Cell Culture Products

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Cell Culture Products

Figure 2:Western blot analysis using KAT7 mAb against human KAT7 (AA: 1-200) recombinant protein. (Expected MW is 48.1 kDa)

Western Blot

Cell Culture Products

Figure 3:Western blot analysis using KAT7 mAb against HEK293 (1) and KAT7 (AA: 1-200)-hIgGFc transfected HEK293 (2) cell lysate.

Western Blot

Cell Culture Products

Figure 4:Western blot analysis using KAT7 mouse mAb against MOLT4 (1), COS7 (2), F9 (3), HepG2 (4), PC-2 (5), U251 (6), MCF-7 (7), and NIH/3T3 (8) cell lysate.

Product Overview
Description

The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016]

References (references)
References (references) 1.Biochem Biophys Res Commun. 2017 Jul 22;489(2):235-241.
2.Cancer Sci. 2013 Dec;104(12):1647-55.

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