KARS Primary Antibody
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Description
KARS: lysyl-tRNA synthetase. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Western Blot
Figure 1: Western blot analysis using KARS mouse mAb against truncated Trx-KARS recombinant protein (1), truncated MBP-KARS (aa90-174) and full length KARS (aa1-188) transfected CHO-K1 cell lysate (3).
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, showing cytoplasmic localization with DAB staining using KARS mouse mAb.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using KARS mouse mAb
For Research Use Only. Not for use in diagnostic procedures.