JAK2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesJTK10; JAK2
ProductOrderJ
Clone#1C1
Entrez GenelD3717
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
MW130.6kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
745-955
Catalog#: 30041
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Images
Western Blot
Figure 1: Western blot analysis using JAK2 mouse mAb against THP-1(1) cell lysate.
Figure 1: Western blot analysis using JAK2 mouse mAb against THP-1(1) cell lysate.
Product Overview
Description

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

References (references)
References (references)1. Mol Cell Endocrinol. 1997 May 16;129(2):199-208.
2. J Immunol. 1999 Dec 15;163(12):6651-8.
3. J Biol Chem. 1999 Oct 29;274(44):31531-42.