ITGB7

Item Information
Catalog #Size/ConcentrationPrice
Specification
Clone#6A2G4
Entrez GenelD3695
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human ITGB7 (AA: 20-174) expressed in E. Coli.
MW86.9kDa
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/50 - 1/200
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
extra(20-174)
Catalog#: 32285
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using ITGB7 mAb against human ITGB7 (AA: 20-174) recombinant protein. (Expected MW is 43.4 kDa)
Figure 2:Western blot analysis using ITGB7 mAb against human ITGB7 (AA: 20-174) recombinant protein. (Expected MW is 43.4 kDa)
Western Blot
Figure 3:Western blot analysis using ITGB7 mAb against HEK293-6e (1) and ITGB7 (AA: 20-174)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using ITGB7 mAb against HEK293-6e (1) and ITGB7 (AA: 20-174)-hIgGFc transfected HEK293-6e (2) cell lysate.
Immunohistochemical analysis
Figure 4:Immunofluorescence analysis of Hela cells using ITGB7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Figure 4:Immunofluorescence analysis of Hela cells using ITGB7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Immunofluorescence analysis
Figure 5:Flow cytometric analysis of Jurkat cells using ITGB7 mouse mAb (green) and negative control (red).
Figure 5:Flow cytometric analysis of Jurkat cells using ITGB7 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded lung cancer tissues using ITGB7 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded lung cancer tissues using ITGB7 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ITGB7 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ITGB7 mouse mAb with DAB staining.
Product Overview
Description

This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

References (references)
References (references)1.J Immunol. 2000 Oct 15;165(8):4338-45.
2.J Immunol. 2001 Feb 15;166(4):2179-85.