ITGAM Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6
ProductOrderI
Clone#3A10H5
Entrez GenelD3684
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.
MW127.1kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
623-728
Catalog#: 30567
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Images
Western Blot
Figure 1: Western blot analysis using ITGAM mAb against human ITGAM recombinant protein. (Expected MW is 37.5 kDa)
Figure 1: Western blot analysis using ITGAM mAb against human ITGAM recombinant protein. (Expected MW is 37.5 kDa)
Western Blot
Figure 2: Western blot analysis using ITGAM mAb against HEK293 (1) and ITGAM (AA: 623-728)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using ITGAM mAb against HEK293 (1) and ITGAM (AA: 623-728)-hIgGFc transfected HEK293 (2) cell lysate.
Immunofluorescence analysis
Figure 3: Immunofluorescence analysis of Hela cells using ITGAM mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Figure 3: Immunofluorescence analysis of Hela cells using ITGAM mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
References (references)
References (references)1. Ann Rheum Dis. 2012 Dec;71(12):2028-34.
2. J Infect Chemother. 2011 Apr;17(2):291-6.