IL34 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesIL-34; C16orf77; MGC34647; IL34
ProductOrderI
Clone#1D12
Entrez GenelD146433
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human IL34 expressed in E. Coli.
MW27.5kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
21-242
Catalog#: 30071
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using IL34 mAb against IL34-hIgGFc transfected HEK293 cell lysate.
Figure 1: Western blot analysis using IL34 mAb against IL34-hIgGFc transfected HEK293 cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of U251 cells using IL34 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of U251 cells using IL34 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Flow cytometric
Figure 3: Flow cytometric analysis of K562 cells using IL34 mouse mAb (green) and negative control (purple).
Figure 3: Flow cytometric analysis of K562 cells using IL34 mouse mAb (green) and negative control (purple).
Product Overview
Description

Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.Tissue specificity: Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.

References (references)
References (references)1. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24.
2. Lim J, et al. Cell, 2006 May 19.
3. Lin H, et al. Science, 2008 May 9.