IL-2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesAldesleukin; TCGF; interleukin-2
ProductOrderI
Clone#8D5
Entrez GenelD3558
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of IL2 expressed in E. Coli.
MW17.6kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
N
Catalog#: 20316
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Images
Western Blot
Figure 1: Western blot analysis using IL2 mouse mAb against full-length IL2 recombinant protein with Trx tag (1) and full-length IL2-hIgGFc transfected HEK293 cell lysate(2).
Figure 1: Western blot analysis using IL2 mouse mAb against full-length IL2 recombinant protein with Trx tag (1) and full-length IL2-hIgGFc transfected HEK293 cell lysate(2).
Product Overview
Description

IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

References (references)
References (references)1. Leukemia. 2008 Dec;22(12):2201-7.
2. J Immunol. 2008 Feb 1;180(3):1490-8.