IL-1a Primary Antibody
Item Information
Catalog #
Size
Price
Description
Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease
Product Overview
Entrez GenelD
3552
Aliases
IL1; IL-1A; IL1F1; IL1-ALPHA
Clone#
3A6F11
Host / Isotype
Mouse / IgG2a
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human IL1a expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Du,Y.; et al. 2000. Neurology 55: 480-484.
2. Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.
2. Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.
Product Image
Western Blot
Figure 1: Western blot analysis using IL1a mouse mAb against truncated IL1a recombinant protein.
For Research Use Only. Not for use in diagnostic procedures.