IFNGR1

Item Information

Catalog #

Size

Price

Description

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

Product Overview

Entrez GenelD

3459

Aliases

CD119; IFNGR; IMD27A; IMD27B

Clone#

3B2D4

Host / Isotype

Mouse / Mouse IgG2b

Species Reactivity

Human

Immunogen

Purified recombinant fragment of human IFNGR1 (AA: extra 18-245) expressed in HEK293-6e cells supernatant.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

4℃; -20℃ for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

ICC (Immunocytochemistry)

1/50 - 1/200

FCM (Flow Cytometry)

1/200 - 1/400

ELISA

1/10000

References

1.Cell Mol Gastroenterol Hepatol. 2021;12(2):465-487.
2.J Clin Immunol. 2021 May;41(4):834-836.

Product Image

Elisa

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using IFNGR1 mAb against human IFNGR1 (AA:extra 18-245) recombinant protein. (Expected MW is 56.3 kDa)

Immunohistochemical analysis

Figure 3:Immunofluorescence analysis of Hela cells using IFNGR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Immunofluorescence analysis