ICAM1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesBB2; CD54; P3.58; ICAM1
ProductOrderI
Clone#6G12
Entrez GenelD3383
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.
MW57.8kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
28-480
Catalog#: 30030
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Images
Western Blot
Figure 1: Western blot analysis using ICAM1 mouse mAb against ICAM1(AA: 28-480)-hIgGFc transfected HEK293 (1) cell lysate.
Figure 1: Western blot analysis using ICAM1 mouse mAb against ICAM1(AA: 28-480)-hIgGFc transfected HEK293 (1) cell lysate.
Product Overview
Description

ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

References (references)
References (references)1. J Neurosci Res. 1992 Feb;31(2):365-74.
2. J Cell Biol. 2002 Jun 24;157(7):1233-45.
3. J Hepatol. 2004 Mar;40(3):375-9.