human Splunc2 Primary Antibody
|Aliases||BPIFA2; PSP; SPLUNC2; C20orf70; bA49G10.1|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human Splunc2 (AA: 16-250) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using Splunc2 mAb against human Splunc2 recombinant protein. (Expected MW is 27.6 kDa)
Figure 2: Western blot analysis using Splunc2 mAb against HEK293 (1) and Splunc2 (AA: 16-250)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Flow cytometric analysis of A549 cells using Splunc2 mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||SPLUNC2 is one member of PLUNC family, the gene undergoes alternative splicing using two 5' non-coding exons, suggesting that the gene is regulated by alternative promoters.multiple SPLUNC2 isoforms are found in the oral cavity and suggest that these proteins may be differentially regulated in distinct tissues where they may function in the innate immune response. Mucin plugs, mucous and intermediate cells of mucoepidermoid carcinomas were positive for LPLUNC1 and SPLUNC2, but areas composed of epidermoid and clear cells were negative for all PLUNCs. Papillary cystadenocarcinoma was positive for all PLUNCs. |
|References (references)||1.Histochem Cell Biol. 2009 Sep;132(3):339-49. |
2.Oral Dis. 2008 Oct;14(7):613-9.