HSF4 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCTM
ProductOrderH
Clone#2E7
Entrez GenelD3299
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human HSF4 expressed in E. Coli.
MW53kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
245-411
Catalog#: 30350
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Images
Western Blot
Figure 1: Western blot analysis using HSF4 mAb against human HSF4 (AA: 245-411) recombinant protein. (Expected MW is 42.9 kDa)
Figure 1: Western blot analysis using HSF4 mAb against human HSF4 (AA: 245-411) recombinant protein. (Expected MW is 42.9 kDa)
Flow cytometric
Figure 2: Flow cytometric analysis of HeLa cells using HSF4 mouse mAb (green) and negative control (red).
Figure 2: Flow cytometric analysis of HeLa cells using HSF4 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

References (references)
References (references)Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2010 Apr;26(4):325-8.
Am J Hum Genet. 2009 Nov;85(5):628-42.