HPRT Primary Antibody
Item Information
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Description
The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy . This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.
Product Overview
Clone#
1F8D11
Species Reactivity
Human
Immunogen
Purified recombinant fragment of HPRT expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Manjanatha MG, et.al Mutat Res. 2004 Mar 22;547(1-2):5-18.
Product Image
Western Blot
Figure 1: Western blot analysis using HPTR mouse mAb against truncated HPRT recombinant protein.
For Research Use Only. Not for use in diagnostic procedures.