HOXB4 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHOX2; HOX2F; HOX-2.6
ProductOrderH
Clone#3A2D4
Entrez GenelD3214
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG2a
ImmunogenPurified recombinant fragment of human HOXB4 (AA: 16-251) expressed in E. Coli.
MW27.6kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
16-251
Catalog#: 30643
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Images
Western Blot
Figure 1: Western blot analysis using HOXB4 mAb against human HOXB4 (AA: 16-251) recombinant protein. (Expected MW is 51.9 kDa)
Figure 1: Western blot analysis using HOXB4 mAb against human HOXB4 (AA: 16-251) recombinant protein. (Expected MW is 51.9 kDa)
Western Blot
Figure 2: Western blot analysis using HOXB4 mAb against HEK293 (1) and HOXB4 (AA: 16-251)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using HOXB4 mAb against HEK293 (1) and HOXB4 (AA: 16-251)-hIgGFc transfected HEK293 (2) cell lysate.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.

References (references)
References (references)1. Blood. 2012 May 10;119(19):e139-47.
2. J Cancer Res Clin Oncol. 2012 Feb;138(2):293-300.