HOXB4 Primary Antibody
|Aliases||HOX2; HOX2F; HOX-2.6|
|Formulation||Purified antibody in PBS with 0.05% sodium azide.|
|Immunogen||Purified recombinant fragment of human HOXB4 (AA: 16-251) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using HOXB4 mAb against human HOXB4 (AA: 16-251) recombinant protein. (Expected MW is 51.9 kDa)
Figure 2: Western blot analysis using HOXB4 mAb against HEK293 (1) and HOXB4 (AA: 16-251)-hIgGFc transfected HEK293 (2) cell lysate.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
|References (references)||1. Blood. 2012 May 10;119(19):e139-47.|
2. J Cancer Res Clin Oncol. 2012 Feb;138(2):293-300.