HDAC9 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL
ProductOrderH
Clone#2B7C4
Entrez GenelD9734
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human HDAC9 (AA: 343-569) expressed in E. Coli.
MW111.3kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
343-569
Catalog#: 30822
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using HDAC9 mAb against human HDAC9 (AA: 343-569) recombinant protein. (Expected MW is 50.5 kDa)
Figure 2:Western blot analysis using HDAC9 mAb against human HDAC9 (AA: 343-569) recombinant protein. (Expected MW is 50.5 kDa)
Western Blot
Figure 3:Western blot analysis using HDAC9 mAb against HEK293 (1) and HDAC9 (AA:343-569)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using HDAC9 mAb against HEK293 (1) and HDAC9 (AA:343-569)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Hela cells using HDAC9 mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of Hela cells using HDAC9 mouse mAb (green) and negative control (red).
Product Overview
DescriptionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
References (references)
References (references)1.Int J Clin Exp Pathol. 2013 Dec 15;7(1):213-20.
2.J Biol Chem. 2011 Jan 21;286(3):2343-53.
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