HDAC6 Primary Antibody
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using HDAC6 mAb against human HDAC6 (AA: 482-800) recombinant protein. (Expected MW is 60.6 kDa)
Figure 3:Western blot analysis using HDAC6 mAb against HEK293 (1) and HDAC6 (AA: 482-800)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Flow cytometric analysis of Hela cells using HDAC6 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.