HDAC2 Primary Antibody
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 2:Western blot analysis using HDAC2 mAb against human HDAC2 (AA: 217-327) recombinant protein. (Expected MW is 38.1 kDa)
Figure 3:Western blot analysis using HDAC2 mAb against HEK293 (1) and HDAC2 (AA: 217-327)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using HDAC2 mouse mAb against Hela (1), Jurat (2), HepG2 (3), Hek293 (4), K562 (5), MCF-7 (6), NIH3T3 (7), COS7 (8) and PC-12 (9) cell lysate.
Figure 5:Flow cytometric analysis of Hela cells using HDAC2 mouse mAb (green) and negative control (red).
Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using HDAC2 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.