HDAC2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHD2; RPD3; YAF1
ProductOrderH
Clone#4C10C3
Entrez GenelD3066
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human HDAC2 (AA: 217-327) expressed in E. Coli.
MW55.4kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
217-327
Catalog#: 30828
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using HDAC2 mAb against human HDAC2 (AA: 217-327) recombinant protein. (Expected MW is 38.1 kDa)
Figure 2:Western blot analysis using HDAC2 mAb against human HDAC2 (AA: 217-327) recombinant protein. (Expected MW is 38.1 kDa)
Western Blot
Figure 3:Western blot analysis using HDAC2 mAb against HEK293 (1) and HDAC2 (AA: 217-327)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using HDAC2 mAb against HEK293 (1) and HDAC2 (AA: 217-327)-hIgGFc transfected HEK293 (2) cell lysate.
Product Overview
DescriptionThis gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
References (references)
References (references)1.Zhonghua Bing Li Xue Za Zhi. 2012 Jul;41(7):466-9.
2.J Cell Biochem. 2012 Jun;113(6):2167-77.