HAND1 Primary Antibody
Item Information
Catalog #
Size
Price
Description
HAND1: heart and neural crest derivatives expressed 1. The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Product Overview
Entrez GenelD
9421
Aliases
Hxt; eHand; Thing1; bHLHa27
Clone#
8E7A11
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. J Biol Chem. 2002 Apr 12;277(15):12604-12.
2. Mol Cell. 2003 Nov;12(5):1225-37.
2. Mol Cell. 2003 Nov;12(5):1225-37.
Product Image
Western Blot
Figure 1: Western blot analysis using HAND1 mouse mAb against truncated Trx-HAND1 recombinant protein (1).
For Research Use Only. Not for use in diagnostic procedures.