GSN Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Product Overview
Entrez GenelD
2934
Aliases
ADF; AGEL
Clone#
5E3B9
Host / Isotype
Mouse / Mouse IgG1
Immunogen
Purified recombinant fragment of human GSN (AA: (673-783)) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200-1/1000
FCM (Flow Cytometry)
1/200-1/400
ELISA
1/10000
References
1,Transl Res.2018 Dec;202:109-119;2,Case Reports Brain Behav.2018 Dec;8(12):e01151.
Product Image
ELISA
![Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-elisa_31930ea_459.jpg?v=1666704946)
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
WESTERN BLOT
![Figure 2: Western blot analysis using GSN mAb against human GSN (AA: 2x(673-783)) recombinant protein. (Expected MW is 28.4 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-wb_31930rwb_460.jpg?v=1666704946)
Figure 2: Western blot analysis using GSN mAb against human GSN (AA: 2x(673-783)) recombinant protein. (Expected MW is 28.4 kDa)
WESTERN BLOT
![Figure 3: Western blot analysis using GSN mAb against HEK293-6e (1) and GSN (AA: 673-783)-hIgG Fc transfected HEK293-6e (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-wb_31930twb_461.jpg?v=1666704946)
Figure 3: Western blot analysis using GSN mAb against HEK293-6e (1) and GSN (AA: 673-783)-hIgG Fc transfected HEK293-6e (2) cell lysate.
FLOW CYTOMETRY
![Figure 4: Flow cytometric analysis of Jurkat cells using GSN mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-fcm_31930fcm_462.jpg?v=1666704946)
Figure 4: Flow cytometric analysis of Jurkat cells using GSN mouse mAb (green) and negative control (red).
FLOW CYTOMETRY
![Figure 5: Flow cytometric analysis of THP-1 cells using GSN mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-fcm_31930fcm-2_463.jpg?v=1666704946)
Figure 5: Flow cytometric analysis of THP-1 cells using GSN mouse mAb (green) and negative control (red).
IMMUNOHISTOCHEMISTRY
![Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using GSN mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-icc_31930ihc-1_464.jpg?v=1666704946)
Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using GSN mouse mAb with DAB staining.
IMMUNOHISTOCHEMISTRY
![Figure 7: Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using GSN mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/graph-icc_31930ihc-2_465.jpg?v=1666704946)
Figure 7: Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using GSN mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.