GSK3B Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
ProductOrderG
Clone#3D6B4
Entrez GenelD2932
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human GSK3B (AA: 2-159) expressed in E. Coli.
MW46.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
2-159
Catalog#: 30705
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Images
Western Blot
Figure 1: Western blot analysis using GSK3B mAb against human GSK3B (AA: 2-159) recombinant protein. (Expected MW is 20.3 kDa)
Figure 1: Western blot analysis using GSK3B mAb against human GSK3B (AA: 2-159) recombinant protein. (Expected MW is 20.3 kDa)
Flow cytometric
Figure 2: Flow cytometric analysis of NIH/3T3 cells using GSK3B mouse mAb (green) and negative control (red).
Figure 2: Flow cytometric analysis of NIH/3T3 cells using GSK3B mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using GSK3B mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using GSK3B mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using GSK3B mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using GSK3B mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References (references)
References (references)1. Int J Cancer. 2013 Aug 15;133(4):807-15.
2. Blood. 2012 Mar 8;119(10):2335-45.