GRIK3 Primary Antibody
Item Information
Catalog #
Size
Price
Description
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
Product Overview
Entrez GenelD
2899
Aliases
EAA5; GLR7; GLUR7; GluK3; GluR7a
Clone#
2B4H1
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human GRIK3 (AA: extra 32-173) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Eur Addict Res. 2013;19(1):55-9.
2.Psychiatr Pol. 2011 May-Jun;45(3):325-35.
2.Psychiatr Pol. 2011 May-Jun;45(3):325-35.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using GRIK3 mAb against human GRIK3 (AA: extra 32-173) recombinant protein. (Expected MW is 42 kDa)
Western Blot
Figure 3:Western blot analysis using GRIK3 mAb against HEK293 (1) and GRIK3 (AA: extra 32-173)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using GRIK3 mouse mAb against A431 (1) and Hela (2) cell lysate.
Flow cytometric
Figure 5:Flow cytometric analysis of Hela cells using GRIK3 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.