GRIA2 Primary Antibody

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Description

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Image
Western Blot
Figure 1: Western blot analysis using GRIA2 mAb against human GRIA2 recombinant protein. (Expected MW is 43 kDa)
Figure 1: Western blot analysis using GRIA2 mAb against human GRIA2 recombinant protein. (Expected MW is 43 kDa)
Western Blot
Figure 2: Western blot analysis using GRIA2 mAb against HEK293 (1) and GRIA2 (AA: 652-807)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using GRIA2 mAb against HEK293 (1) and GRIA2 (AA: 652-807)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 3: Western blot analysis using GRIA2 mouse mAb against HeLa (1) cell lysate.
Figure 3: Western blot analysis using GRIA2 mouse mAb against HeLa (1) cell lysate.
Flow cytometric
Figure 4: Flow cytometric analysis of SK-N-SH cells using GRIA2 mouse mAb (green) and negative control (red).
Figure 4: Flow cytometric analysis of SK-N-SH cells using GRIA2 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.