FOXP3 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesJM2; AIID; IPEX; PIDX; XPID; DIETER; MGC141961; MGC141963; FOXP3
ProductOrderF
Clone#4C7
Entrez GenelD50943
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human FOXP3 expressed in E. Coli.
MW47.2kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
2-193
Catalog#: 30062
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Images
Western Blot
Figure 1: Western blot analysis using FOXP3 mAb against FOXP3(AA: 2-193)-hIgGFc transfected HEK293 cell.
Figure 1: Western blot analysis using FOXP3 mAb against FOXP3(AA: 2-193)-hIgGFc transfected HEK293 cell.
Product Overview
Description

FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

References (references)
References (references)1. Clin Immunol. 2010 Mar;134(3):277-88.
2. Lupus. 2010 Feb;19(2):138-45.