FOXP3 Primary Antibody
Item Information
Catalog #
Size
Price
Description
FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Product Overview
Entrez GenelD
50943
Aliases
JM2; AIID; IPEX; PIDX; XPID; DIETER; MGC141961; MGC141963; FOXP3
Clone#
4C7
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human FOXP3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Clin Immunol. 2010 Mar;134(3):277-88.
2. Lupus. 2010 Feb;19(2):138-45.
2. Lupus. 2010 Feb;19(2):138-45.
Product Image
Western Blot
Figure 1: Western blot analysis using FOXP3 mAb against FOXP3(AA: 2-193)-hIgGFc transfected HEK293 cell.
For Research Use Only. Not for use in diagnostic procedures.