FOXA2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHNF3B; TCF3B; MGC19807
ProductOrderF
Clone#7H4B7
Entrez GenelD3170
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of FOXA2 expressed in E. Coli.
MW48kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
aa242-457
Catalog#: 20375
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using FOXA2 mouse mAb against A549 (1) cell lysate.
Figure 1: Western blot analysis using FOXA2 mouse mAb against A549 (1) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human colon cancer (A), gastric cancer (B) and rectal cancer (C) tissues using FOXA2 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded human colon cancer (A), gastric cancer (B) and rectal cancer (C) tissues using FOXA2 mouse mAb with DAB staining.
Product Overview
Description

FOXA2 (forkhead box A2), also known as HNF3B (hepatocyte nuclear factor 3, beta). It is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for FOXA2.

References (references)
References (references)1. Hepatology. 2008 Aug;48(2):597-606.
2. Cancer Res. 2004 Jun 15;64(12):4137-47.