FOXA2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
FOXA2 (forkhead box A2), also known as HNF3B (hepatocyte nuclear factor 3, beta). It is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for FOXA2.
Product Overview
Entrez GenelD
3170
Aliases
HNF3B; TCF3B; MGC19807
Clone#
7H4B7
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of FOXA2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Hepatology. 2008 Aug;48(2):597-606.
2. Cancer Res. 2004 Jun 15;64(12):4137-47.
2. Cancer Res. 2004 Jun 15;64(12):4137-47.
Product Image
Western Blot
Figure 1: Western blot analysis using FOXA2 mouse mAb against A549 (1) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human colon cancer (A), gastric cancer (B) and rectal cancer (C) tissues using FOXA2 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.