FOS Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
Aliasesp55; AP-1; C-FOS
ProductOrderF
Clone#2G2
Entrez GenelD2353
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human FOS expressed in E. Coli.
MW40.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
116-298
Catalog#: 30360
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Images
Western Blot
Figure 1: Western blot analysis using FOS mAb against human FOS (AA: 116-298) recombinant protein. (Expected MW is 45.8 kDa)
Figure 1: Western blot analysis using FOS mAb against human FOS (AA: 116-298) recombinant protein. (Expected MW is 45.8 kDa)
Western Blot
Figure 2: Western blot analysis using FOS mouse mAb against HeLa (1), and HeLa (2) cell lysate.
Figure 2: Western blot analysis using FOS mouse mAb against HeLa (1), and HeLa (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using FOS mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using FOS mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded cerebellum tissues using FOS mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded cerebellum tissues using FOS mouse mAb with DAB staining.
Flow cytometric
Figure 5: Flow cytometric analysis of HeLa cells using FOS mouse mAb (green) and negative control (red).
Figure 5: Flow cytometric analysis of HeLa cells using FOS mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

References (references)
References (references)Mol Cell Biochem. 2010 Apr;337(1-2):53-63.
Cancer Invest. 2009 Oct;27(8):816-24.