FOLR1 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31397 100μl $341.00
Specification
AliasesFBP; FOLR
Product OrderF
Clone#2G5C12
Entrez GeneID2348
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG2a
ImmunogenPurified recombinant fragment of human FOLR1 (AA: 41-227) expressed in E. Coli.
MW29.8kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C.  Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/100 - 1/500
IHC_P (Immunohistochemistry) 1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
Sequence
41-227
Catalog
31397
$341.00
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Images

Elisa

Cell Culture Products
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Cell Culture Products
Figure 2:Western blot analysis using FOLR1 mAb against human FOLR1 (AA: 41-227) recombinant protein. (Expected MW is 48 kDa)

Western Blot

Cell Culture Products
Figure 3:Western blot analysis using FOLR1 mAb against HEK293 (1) and FOLR1 (AA: 41-227)-hIgGFc transfected HEK293 (2) cell lysate.

Immunofluorescence analysis

Cell Culture Products
Figure 4:Immunofluorescence analysis of Hela cells using FOLR1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric

Cell Culture Products
Figure 5:Flow cytometric analysis of Hela cells using FOLR1 mouse mAb (green) and negative control (red).

Immunohistochemical analysis

Cell Culture Products
Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using FOLR1 mouse mAb with DAB staining.

Immunohistochemical analysis

Cell Culture Products
Figure 7:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using FOLR1 mouse mAb with DAB staining.
Product Overview
Description

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

References (references)
References (references) 1.Biosens Bioelectron. 2016 Apr 15;78:147-53.
2.PLoS One. 2015 Mar 27;10(3):e0122209.

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