FLT1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesFLT; VEGFR1
ProductOrderF
Clone#3D10
Entrez GenelD2321
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.
MW100kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
Extra(27-656)100.9
Catalog#: 20387
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Images
Western Blot
Figure 1: Western blot analysis using FLT1 mouse mAb against extracellular domain of human FLT1.
Figure 1: Western blot analysis using FLT1 mouse mAb against extracellular domain of human FLT1.
Product Overview
Description

Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), also known as FLT1 or VEGFR-1. It is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

References (references)
References (references)1. Mol Med. 2006 Jul-Aug;12(7-8):127-36.
2. Oncogene. 1997 May 29;14(21):2553-61.