FGF4 Primary Antibody
|Aliases||HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-5|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of humanFGF4 (AA: 62-123) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|WB (Western Blot)||1/500 - 1/2000|
Contact us to order
Figure 1: Western blot analysis using FGF4 mAb against human FGF4 recombinant protein. (Expected MW is 32.6 kDa)
Figure 2: Western blot analysis using FGF4 mAb against HEK293 (1) and FGF4 (AA: 62-123)-hIgGFc transfected HEK293 (2) cell lysate.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
|References (references)||1.PLoS One. 2009;4(3):e4794. |
2.Stem Cells. 2008 Mar;26(3):767-74.