FGB Primary Antibody
Item Information
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Price
Description
Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Product Overview
Entrez GenelD
2244
Aliases
fibrinogen beta chain
Clone#
1F9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Blood. 2003 Dec 15;102(13):4413-5.
2. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):758-63.
2. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):758-63.
Product Image
Western Blot
Figure 1: Western blot analysis using FGB mouse mAb against human plasma (1).
For Research Use Only. Not for use in diagnostic procedures.