FGB Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
Aliasesfibrinogen beta chain
ProductOrderF
Clone#1F9
Entrez GenelD2244
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.
MW52kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
30-300
Catalog#: 20348
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Images
Western Blot
Figure 1: Western blot analysis using FGB mouse mAb against human plasma (1).
Figure 1: Western blot analysis using FGB mouse mAb against human plasma (1).
Product Overview
Description

Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

References (references)
References (references)1. Blood. 2003 Dec 15;102(13):4413-5.
2. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):758-63.