FBXL10 Primary Antibody
|Aliases||CXXC2; Fbl10; PCCX2; FBXL10; JHDM1B|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human FBXL10 (AA: 457-555) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 2:Western blot analysis using FBXL10 mAb against human FBXL10 (AA: 457-555) recombinant protein. (Expected MW is 36.8 kDa)
Figure 3:Western blot analysis using FBXL10 mAb against HEK293 (1) and FBXL10 (AA: 457-555)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Flow cytometric analysis of HeLa cells using FBXL10 mouse mAb (green) and negative control (red).
|Description||This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.|
|References (references)||1.Cancer Res. 2014 Jul 15;74(14):3935-46. |
2.Elife. 2012 Dec 18;1:e00205.