FBLN5 Primary Antibody

Item Information
Catalog # Size/Concentration Price
20197 100μl $352.00
Specification
AliasesEVEC; UP50; ARMD3; DANCE
Product OrderF
Clone#1G6A4
Entrez GeneID10516
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.\
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C.  Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P (Immunohistochemistry) 1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
N/A
Catalog
20197
$352.00
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+

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Images

Western Blot

Cell Culture Products
Figure 1: Western blot analysis using FBLN5 mouse mAb against truncated FBLN5-His recombinant protein.

Immunohistochemical analysis

Cell Culture Products
Figure 2: Immunohistochemical analysis of paraffin-embedded human colon cancer (left) and breast cancer (right) showing cytoplasmic localization with DAB staining using FBLN5 mouse mAb.
Product Overview
Description FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.
References (references)
References (references) 1. Am J Hum Genet. 2003 Apr;72(4):998-1004.
2. Genome Res. 2003 Oct;13(10):2265-70
3. N Engl J Med. 2004 Jul 22;351(4):346-53.
4. Surgery. 2005 Aug;138(2):352-9.

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