FBLN5 Primary Antibody
Item Information
Catalog #
Size
Price
Description
FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.
Product Overview
Entrez GenelD
10516
Aliases
EVEC; UP50; ARMD3; DANCE
Clone#
1G6A4
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Am J Hum Genet. 2003 Apr;72(4):998-1004.
2. Genome Res. 2003 Oct;13(10):2265-70
3. N Engl J Med. 2004 Jul 22;351(4):346-53.
4. Surgery. 2005 Aug;138(2):352-9.
2. Genome Res. 2003 Oct;13(10):2265-70
3. N Engl J Med. 2004 Jul 22;351(4):346-53.
4. Surgery. 2005 Aug;138(2):352-9.
Product Image
Western Blot
Figure 1: Western blot analysis using FBLN5 mouse mAb against truncated FBLN5-His recombinant protein.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human colon cancer (left) and breast cancer (right) showing cytoplasmic localization with DAB staining using FBLN5 mouse mAb.
For Research Use Only. Not for use in diagnostic procedures.