FABP4 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesaP2; A-FABP; FABP4
ProductOrderF
Clone#9B8D
Entrez GenelD2167
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of FABP4 expressed in E. Coli.
MW14kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
full 1-132
Catalog#: 20409
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Images
Western Blot
Figure 1: Western blot analysis using FABP4 mouse mAb against FABP4-hIgGFc transfected HEK293 cell lysate.
Figure 1: Western blot analysis using FABP4 mouse mAb against FABP4-hIgGFc transfected HEK293 cell lysate.
Product Overview
Description

Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.

References (references)
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2. Science. 1996. 274:1377-79.
3. Biochemistry. 1997.36(27):8311-7
4. Mol Cell Biochem. 2004.302(1-2):203-13