EZH2 Primary Antibody
|Aliases||WVS; ENX1; EZH1; KMT6; WVS2; ENX-1; EZH2b; KMT6A|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human EZH2 (AA: 1-194) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 2:Western blot analysis using EZH2 mAb against human EZH2 (AA: 1-194) recombinant protein. (Expected MW is 48.5 kDa)
Figure 3:Western blot analysis using EZH2 mAb against HEK293 (1) and EZH2 (AA: 1-194)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Flow cytometric analysis of Hela cells using EZH2 mouse mAb (green) and negative control (red).
Figure 5:Immunohistochemical analysis of paraffin-embedded lung cancer tissues using EZH2 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded colon cancer tissues using EZH2 mouse mAb with DAB staining.
|Description||This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.|
|References (references)||Int J Gynecol Cancer. 2013 Jul;23(6):997-1005.|
Cell Cycle. 2013 Jul 1;12(13):2113-9.