ETV1 Primary Antibody

Item Information

Catalog #

Size

Price

Description

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

Product Overview

Entrez GenelD

2115

Aliases

ER81

Clone#

1C8B6

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

ELISA

1/10000

References

1. Neoplasia. 2006 Oct;8(10):826-32.
2. Cancer Genet Cytogenet. 2008 May;183(1):21-7.

Product Image

Western Blot

Figure 1: Western blot analysis using ETV1 mouse mAb against truncated Trx-ETV1 recombinant protein (1) and full-length ETV1 (aa1-477)-hIgGFc transfected CHO-K1 cell lysate(2).

Western Blot

Figure 2: Western blot analysis using ETV1 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ETV1 cDNA (2).

For Research Use Only. Not for use in diagnostic procedures.