ESRRA Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene.
Product Overview
Entrez GenelD
2101
Aliases
ERR1; ERRa; ESRL1; NR3B1; ERRalpha
Clone#
6F1E6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human, Rat
Immunogen
Purified recombinant fragment of human ESRRA (AA: 198-376) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.J Huazhong Univ Sci Technolog Med Sci. 2014 Dec;34(6):875-81.
2.Mol Ther. 2014 Apr;22(4):743-51.
2.Mol Ther. 2014 Apr;22(4):743-51.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using ESRRA mAb against human ESRRA (AA: 198-376) recombinant protein. (Expected MW is 45.3 kDa)
Western Blot
Figure 3:Western blot analysis using ESRRA mAb against HEK293 (1) and ESRRA (AA: 198-376)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using ESRRA mouse mAb against C6 (1) cell lysate.
Flow cytometric
Figure 5:Flow cytometric analysis of Hela cells using ESRRA mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.