ESR1 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Product Overview
Entrez GenelD
2099
Aliases
ER; ESR; Era; ESRA; NR3A1; DKFZp686N23123; ESR1
Clone#
6B6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human ESR1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ICC (Immunocytochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Calcif Tissue Int. 2010 Jul;87(1):25-35.
2. Arch Gynecol Obstet. 2010 Jun 18.
3. Biochemistry. 2010 Jul 27;49(29):5978-88.
2. Arch Gynecol Obstet. 2010 Jun 18.
3. Biochemistry. 2010 Jul 27;49(29):5978-88.
Product Image
Western Blot
Figure 1: Western blot analysis using ESR1 mouse mAb against MCF-7 (1), T47D (2) and SKBR3 (3) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues using ESR1 mouse mAb with DAB staining.
Immunofluorescence analysis
Figure 3: Immunofluorescence analysis of Hela cells using ESR1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
For Research Use Only. Not for use in diagnostic procedures.