ERN1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesIRE1; IRE1P; IRE1a; hIRE1p; FLJ30999; MGC163277; MGC163279; ERN1
ProductOrderE
Clone#9F2
Entrez GenelD2081
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.
MW109kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
282-433
Catalog#: 30026
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Images
Western Blot
Figure 1: Western blot analysis using ERN1 mouse mAb against Raji (1), A431 (2), Jurkat (3), Hela(4) and HEK293 (5) cell lysate.
Figure 1: Western blot analysis using ERN1 mouse mAb against Raji (1), A431 (2), Jurkat (3), Hela(4) and HEK293 (5) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain tissue (A) and stomach tissue (B), showing cytoplasmic localization using ERN1 mouse mAb with DAB staining.
Figure 2: Immunohistochemical analysis of paraffin-embedded human brain tissue (A) and stomach tissue (B), showing cytoplasmic localization using ERN1 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded human Placenta tissues using ERN1 mouse mAb
Figure 3: Immunohistochemical analysis of paraffin-embedded human Placenta tissues using ERN1 mouse mAb
Product Overview
Description

The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

References (references)
References (references)1. Biochem Biophys Res Commun. 2004 Apr 30;317(2):390-6.
2. Mol Cell Biol. 2005 Sep;25(17):7522-33.
3. Science. 2007 Nov 9;318(5852):944-9.