EPHB4 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHTK; MYK1; TYRO11
ProductOrderE
Clone#5B5
Entrez GenelD2050
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.
MW108kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
Extra(16-539)
Catalog#: 20334
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Images
Western Blot
Figure 1: Western blot analysis using EphB4 mouse mAb against extracellular domain of human EphB4 (aa16-539).
Figure 1: Western blot analysis using EphB4 mouse mAb against extracellular domain of human EphB4 (aa16-539).
Immunofluorescence analysis
Figure 2: Confocal Immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with EphB4-hIgGFc using EphB4 mouse mAb (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
Figure 2: Confocal Immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with EphB4-hIgGFc using EphB4 mouse mAb (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
Product Overview
Description

EphB4: EPH receptor B4, also known as Htk, Myk1, Tyro11. Entrez Protein: NP_004435. It is a member of the Eph receptor family, which bind the ephrin ligand family. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.

References (references)
References (references)1. Br J Cancer. 2007 Apr 10;96(7):1083-91.
2. Dig Liver Dis. 2007 Aug;39(8):725-32.