EphB4 Primary Antibody

Item Information
Catalog #
Size
Price
Description

EphB4: EPH receptor B4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Product Overview
Entrez GenelD
2050
Aliases
HTK; MYK1; TYRO11
Clone#
7H4A6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of EphB4 (aa562-612)expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Biochem Biophys Res Commun. 2004 Aug 27;321(3):681-7.
2. Cancer Res. 2005 Jun 1;65(11):4623-32.
3. Development. 2005 Sep;132(18):4097-106.
Product Image
Western Blot
Figure 1: Western blot analysis using EphB4 mouse mAb against Jurkat (1) and HEK293 (2) cell lysate.
Figure 1: Western blot analysis using EphB4 mouse mAb against Jurkat (1) and HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.