EDA2R Primary Antibody

Item Information
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Size
Price
Description

The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016]

Product Overview
Entrez GenelD
60401
Aliases
XEDAR; EDAA2R; EDA-A2R; TNFRSF27
Clone#
4A6B4
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human EDA2R (AA: extra 1-138) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Br J Dermatol. 2012 Jun;166(6):1314-8.
2.Hum Biol. 2012 Dec;84(6):641-94.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using EDA2R mAb against human EDA2R (AA: extra 1-138) recombinant protein. (Expected MW is 41.3 kDa)
Figure 2:Western blot analysis using EDA2R mAb against human EDA2R (AA: extra 1-138) recombinant protein. (Expected MW is 41.3 kDa)
Western Blot
Figure 3:Western blot analysis using EDA2R mAb against HEK293 (1) and EDA2R (AA: extra 1-138)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using EDA2R mAb against HEK293 (1) and EDA2R (AA: extra 1-138)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of MOLT4 cells using EDA2R mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of MOLT4 cells using EDA2R mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.