DYRK4

Item Information
Catalog #Size/ConcentrationPrice
Specification
Clone#4B6G7
Entrez GenelD8798
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human DYRK4 (AA: 303-515) expressed in E. Coli.
MW59.6kDa
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
303-515
Catalog#: 32317
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using DYRK4 mAb against human DYRK4 (AA: 303-515) recombinant protein. (Expected MW is 29 kDa)
Figure 2:Western blot analysis using DYRK4 mAb against human DYRK4 (AA: 303-515) recombinant protein. (Expected MW is 29 kDa)
Western Blot
Figure 3:Western blot analysis using DYRK4 mAb against HEK293-6e (1) and DYRK4 (AA: 303-515)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using DYRK4 mAb against HEK293-6e (1) and DYRK4 (AA: 303-515)-hIgGFc transfected HEK293-6e (2) cell lysate.
Immunofluorescence analysis
Figure 4:Flow cytometric analysis of Hela cells using DYRK4 mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of Hela cells using DYRK4 mouse mAb (green) and negative control (red).
Product Overview
Description

This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

References (references)
References (references)1.J Biol Chem. 2011 Feb 18;286(7):5494-505.
2.Mol Cell Endocrinol. 2007 Mar 15;267(1-2):80-8.