Dynamin-2 Primary Antibody
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Description
Dynamin-2 (Dyn2), with 870-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Western Blot
Figure 1: Western blot analysis using Dynamin2 mouse mAb against truncated Dynamin-2 recombinant protein (1), SKN-SH cell lysate (2) and NIH/3T3 cell lysate (3).
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebrum tissue (left) and myelencephalon tissue (right), showing cytoplasmic localization using Dynamin2 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.