DSG3 Primary Antibody
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Purified antibody in PBS with 0.05% sodium azide.
4°C; -20°C for long term storage
Figure 1: Western blot analysis using DSG3 mAb against human DSG3 (AA: 55-159) recombinant protein. (Expected MW is 37.5 kDa)
Figure 2: Western blot analysis using DSG3 mAb against HEK293 (1) and DSG3 (AA: 55-159)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Western blot analysis using DSG3 mouse mAb against A431 cell lysate.
Figure 4: Flow cytometric analysis of A431 cells using DSG3 mouse mAb (green) and negative control (red).
Figure 5: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using DSG3 mouse mAb with DAB staining.
Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal tissues using DSG3 mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.