DNMT1 Primary Antibody
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using DNMT1 mAb against human DNMT1 (AA: 1317-1616) recombinant protein. (Expected MW is 59.3 kDa)
Figure 3:Western blot analysis using DNMT1 mAb against HEK293 (1) and DNMT1 (AA: 1317-1616)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Immunohistochemical analysis of paraffin-embedded colon cancer tissues using DNMT1 mouse mAb with DAB staining.
Figure 5:Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using DNMT1 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.