DNMT1 Primary Antibody
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Purified antibody in PBS with 0.05% sodium azide
4°C; -20°C for long term storage
Figure 1: Western blot analysis using DNMT1 mAb against human DNMT1 recombinant protein. (Expected MW is 42.6 kDa)
Figure 2: Western blot analysis using DNMT1 mAb against HEK293 (1) and DNMT1 (AA: 1448-1594)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Western blot analysis using IL2RA mouse mAb against Jurkat (1), Cos7 (2), HCT116 (3) and NTERA-2 (4) cell lysate.
Figure 4: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using DNMT1 mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.