This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purified recombinant fragment of human DLL3 (AA: extra 27-226) expressed in E. Coli.
Purified antibody in PBS with 0.05% sodium azide
4℃; -20℃ for long term storage
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using DLL3 mAb against human DLL3 (AA: 27-226) recombinant protein. (Expected MW is 24 kDa)
Figure 3:Western blot analysis using DLL3 mAb against HEK293-6e (1) and DLL3 (AA: 27-226)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 4:Flow cytometric analysis of HEK293 cells using DLL3 mouse mAb (green) and negative control (red).
Figure 5:Immunohistochemical analysis of paraffin-embedded human brain tissues using DLL3 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using DLL3 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.