DLL3

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSCDO1
Clone#6H4C4
Entrez GenelD10683
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG2a
ImmunogenPurified recombinant fragment of human DLL3 (AA: EXTRA(27-226)) expressed in E. Coli.
MW65KDa
Species ReactivityHuman, Rat
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
EXTRA(27-226)
Catalog#: 32306
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using DLL3 mAb against human DLL3 (AA: EXTRA(27-226)) recombinant protein. (Expected MW is 26.5 kDa)
Figure 2:Western blot analysis using DLL3 mAb against human DLL3 (AA: EXTRA(27-226)) recombinant protein. (Expected MW is 26.5 kDa)
Western Blot
Figure 3:Western blot analysis using DLL3 mAb against HEK293-6e (1) and DLL3 (AA: EXTRA(27-226))-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using DLL3 mAb against HEK293-6e (1) and DLL3 (AA: EXTRA(27-226))-hIgGFc transfected HEK293-6e (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using DLL3 mouse mAb against Hela (1)cell lysate.
Figure 4:Western blot analysis using DLL3 mouse mAb against Hela (1)cell lysate.
Immunohistochemical analysis
Figure 5:Immunofluorescence analysis of Hela cells using DLL3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Figure 5:Immunofluorescence analysis of Hela cells using DLL3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Immunofluorescence analysis
Figure 6:Flow cytometric analysis of C6 cells using DLL3 mouse mAb (green) and negative control (red).
Figure 6:Flow cytometric analysis of C6 cells using DLL3 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded cervical carcinoma tissues using DLL3 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded cervical carcinoma tissues using DLL3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 8:Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using DLL3 mouse mAb with DAB staining.
Figure 8:Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using DLL3 mouse mAb with DAB staining.
Product Overview
Description

This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

References (references)
References (references)1,Cancer Sci . 2021 Aug;112(8):2984-2992.
2,Lung Cancer . 2019 Dec;138:102-108.