DKK3 Primary Antibody
Item Information
Catalog #
Size
Price
Description
Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.
Product Overview
Entrez GenelD
27122
Aliases
RIG; REIC
Clone#
4G7
Host / Isotype
Mouse / IgG1
Species Reactivity
Human, Monkey
Immunogen
Purified recombinant fragment of human DKK3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. Virchows Arch. 2009 Jun;454(6):639-46.
2. Gene. 2002 Jan 9;282(1-2):151-8.
3. J Urol. 2004 Mar;171(3):1314-8.
2. Gene. 2002 Jan 9;282(1-2):151-8.
3. J Urol. 2004 Mar;171(3):1314-8.
Product Image
Western Blot
Figure 1: Western blot analysis using DKK3 mouse mAb against HEK293 (1), MCF-7 (2) and HL7702 (3) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of MCF-7 cells using anti-DKK3 mAb (green) and negative control (purple).
For Research Use Only. Not for use in diagnostic procedures.